Drugstore Cowboy is a 1989 American crime drama film directed by the American filmmaker Gus Van Sant. Matt Dillon plays the leader of a group of dopeheads who wander around the country robbing pharmacies to feed their habits. Dillon’s chums include doltish James Le Gros and teen-age junkie Heather Graham; also along for the ride is Dillon’s wife Kelly Lynch. Their nemesis is cop James Remar, whom Dillon takes perverse delight in humiliating. Written by Van Sant and Daniel Yost, and based on an autobiographical novel by James Fogle, the film stars Matt Dillon, Kelly Lynch, Heather Graham and William S. Burroughs. It was Van Sant’s second film as director. At the time the film was made, the source novel by Fogle was unpublished. It was later published in 1990, by which time Fogle had been released from prison. Fogle, like the characters in his story, was a long-time drug user and dealer.